» Thu Jul 22, 2010 3:07 pm
Putting your issues with the weather aside, the mere fact you can't save your game would suggest that you've messed something up big time. I'd suggest completely removing Oblivion and reinstalling, as any other method of fixing is likely going to be longer and more complicated, and less assured of working. Also, the standard line is that autosaves and quicksaves should be disabled, as they're generally bad news for stability and such like.
As for crash-on-load with All Natural disabled, for some reason some people find that their save games are dependent on All Natural - Real Lights.esp. Since this is completely separate from the rest of the mod, you can leave this active when you disable everything else, and then if you want to get rid of it permanently, you can try again later in a different place or something. We don't know why some save games become dependent on it, so we don't know the conditions needed to remove it, but perhaps saving in a cell that's unaffected by RL may do the trick.
If I were you though, I wouldn't bother messing with All Natural until you've got the bigger problem of saving sorted out.
EDIT: On second thought, it sounds like hardware overload or something (overheating perhaps?). I know that if you're getting textures and such disappearing, then it could be Oblivion running out of memory or bugging out due to hardware faults, which would then also cause the crash. Your inability to save could be because of the same thing, so when the game is saved, it finds stuff corrupted and crashes.