This has happened to me before. I'll be playing along and about the time my Lockpicking skill gets to ~29 almost all the doors in all the dungeons become either locked or magically locked. They can be bashed open or opened with a spell but that becomes so tedious that the game isn't worth playing. I can go back to a previous save (2 levels earlier) but the same thing is liable to happen. Anybody know a remedy? (Fixsave doesn't work).

AFAIK, there is no remedy for that.

OK, thanks.