i have OBMM, OBSE loader, wryebash, and the default Oblivion exe as options to launch the game from, and am not sure which I should be using. I have applied the Oblivion 4gb patch (http://www.gamesas.com/index.php?/topic/1078392-oblivion-and-memory-usage/page__hl__Memory%20Usage) which instructed me to to apply the patch to the Oblivion exe and not to the OBSE loader. i do remember reading elsewhere (not sure where) that launching oblivion from the OBSE launcher is preferable. if i do that though, won't i be missing out on the 4GB patch i applied to the Oblvion exe?

what launcher do folks with all the above options use, and why?

thanks.

You need to start the game with obse_loader for it to be active, but obmm will use it if you have it installed and if you check obse enabled in wrye it will do the same, so yeah it doesn't really matter as long as you use one of those three.

ok. so in order to get that 4gig memory patch, do i need to reinstall it onto the obmm or wryebash launcher?

No, just on the original oblivion.exe.

No. OBSE loads up first, gets it's routines working then launches the Oblivion.exe. It's exactly the same as if you were to boot from the default launcher except that OBSE has added more functions that Oblivion will use once it starts up. It doesn't bypass the exe at all, it simply delays it from starting for a few seconds while it does it's thing.