I used to have open cities, but found that it did lag quite a bit near the cities so I deactivated it. I posted my load order anyhow. What's going on?
Spoiler
Oblivion.esm
Jog_X_Mod.esm
All Natural Base.esm
Francesco's Leveled Creatures-Items Mod.esm
Cobl Main.esm
HorseCombatMaster.esm
Unofficial Oblivion Patch.esp
UOP Vampire Aging & Face Fix.esp
Oblivion Citadel Door Fix.esp
DLCShiveringIsles.esp
Unofficial Shivering Isles Patch.esp
All Natural - Real Lights.esp
All Natural.esp
All Natural - SI.esp
MIS.esp
MIS Low Wind.esp
MIS New Sounds Optional Part.esp
AliveWaters.esp
AliveWaters - Koi Addon.esp
AliveWaters - Slaughterfish Addon.esp
PrivateQuarters.esp
MaleBodyReplacerV4.esp
RTFemaleReplacerV12.esp
Thieves Arsenal.esp
Mage Equipment.esp
Ranokoas Organized Potions.esp
Francesco's Optional Files.esp
Cobl Glue.esp
Cobl Si.esp
AdenseEpicDungeon.esp
thievery.esp
VaultsofCyrodiil.esp
DLCFrostcrag.esp
Knights.esp
OCC-KOTN-Patch.esp
xuldarkforest.esp
xulStendarrValley.esp
xulTheHeath.esp
XulEntiusGorge.esp
xulFallenleafEverglade.esp
xulColovianHighlands_EV.esp
xulChorrolHinterland.esp
xulBeachesOfCyrodiilLostCoast.esp
xulBravilBarrowfields.esp
xulLushWoodlands.esp
xulAncientYews.esp
xulAncientRedwoods.esp
xulCloudtopMountains.esp
xulArriusCreek.esp
xulPatch_AY_AC.esp
xulRollingHills_EV.esp
xulPantherRiver.esp
xulRiverEthe.esp
xulBrenaRiverRavine.esp
xulImperialIsle.esp
xulBlackwoodForest.esp
xulCheydinhalFalls.esp
xulAspenWood.esp
xulSkingradOutskirts.esp
Harvest [Flora].esp
Harvest [Flora] - Shivering Isles.esp
Harvest [Flora] - DLCFrostcrag.esp
mmAlchemy3.esp
DropLitTorchOBSE.esp
Dungeon Actors Have Torches 1.6 DT.esp
Improved_potion_of_exploration_11.esp
Quest Award Leveller.esp
Quest Award Leveller - Knights of the Nine.esp
Alternative Start by Robert Evrae.esp
SupremeMagicka.esp
SM_ShiveringIsles.esp
SM_COBL.esp
SM_EnchantStaff.esp
SM_Scrolls.esp
SM_SigilStone.esp
MidasSpells.esp
RenGuardOverhaul.esp
DeadlyReflex 5 - Combat Moves.esp
SM_DeadlyReflex.esp
Oblivion XP.esp
Bald_Hairstyle.esp
Francesco's 7 days respawn time - 1-12 day lenght rescale.esp
Cobl Silent Equip Misc.esp
Bashed Patch, 0.esp
1 hit kills sleeping, knocked out and paralyzed actors.esp
MagicContainer_StandAlone.esp
Rooftop Rewards cleaned.esp
Jog_X_Mod.esm
All Natural Base.esm
Francesco's Leveled Creatures-Items Mod.esm
Cobl Main.esm
HorseCombatMaster.esm
Unofficial Oblivion Patch.esp
UOP Vampire Aging & Face Fix.esp
Oblivion Citadel Door Fix.esp
DLCShiveringIsles.esp
Unofficial Shivering Isles Patch.esp
All Natural - Real Lights.esp
All Natural.esp
All Natural - SI.esp
MIS.esp
MIS Low Wind.esp
MIS New Sounds Optional Part.esp
AliveWaters.esp
AliveWaters - Koi Addon.esp
AliveWaters - Slaughterfish Addon.esp
PrivateQuarters.esp
MaleBodyReplacerV4.esp
RTFemaleReplacerV12.esp
Thieves Arsenal.esp
Mage Equipment.esp
Ranokoas Organized Potions.esp
Francesco's Optional Files.esp
Cobl Glue.esp
Cobl Si.esp
AdenseEpicDungeon.esp
thievery.esp
VaultsofCyrodiil.esp
DLCFrostcrag.esp
Knights.esp
OCC-KOTN-Patch.esp
xuldarkforest.esp
xulStendarrValley.esp
xulTheHeath.esp
XulEntiusGorge.esp
xulFallenleafEverglade.esp
xulColovianHighlands_EV.esp
xulChorrolHinterland.esp
xulBeachesOfCyrodiilLostCoast.esp
xulBravilBarrowfields.esp
xulLushWoodlands.esp
xulAncientYews.esp
xulAncientRedwoods.esp
xulCloudtopMountains.esp
xulArriusCreek.esp
xulPatch_AY_AC.esp
xulRollingHills_EV.esp
xulPantherRiver.esp
xulRiverEthe.esp
xulBrenaRiverRavine.esp
xulImperialIsle.esp
xulBlackwoodForest.esp
xulCheydinhalFalls.esp
xulAspenWood.esp
xulSkingradOutskirts.esp
Harvest [Flora].esp
Harvest [Flora] - Shivering Isles.esp
Harvest [Flora] - DLCFrostcrag.esp
mmAlchemy3.esp
DropLitTorchOBSE.esp
Dungeon Actors Have Torches 1.6 DT.esp
Improved_potion_of_exploration_11.esp
Quest Award Leveller.esp
Quest Award Leveller - Knights of the Nine.esp
Alternative Start by Robert Evrae.esp
SupremeMagicka.esp
SM_ShiveringIsles.esp
SM_COBL.esp
SM_EnchantStaff.esp
SM_Scrolls.esp
SM_SigilStone.esp
MidasSpells.esp
RenGuardOverhaul.esp
DeadlyReflex 5 - Combat Moves.esp
SM_DeadlyReflex.esp
Oblivion XP.esp
Bald_Hairstyle.esp
Francesco's 7 days respawn time - 1-12 day lenght rescale.esp
Cobl Silent Equip Misc.esp
Bashed Patch, 0.esp
1 hit kills sleeping, knocked out and paralyzed actors.esp
MagicContainer_StandAlone.esp
Rooftop Rewards cleaned.esp