A little off topic here but how will perks be distributed? 280 perks and 18 skills give 15.56 for each skill. However I can see far more useful weapon perks than alchemy perks. more so as one handed cover long and short swords, daggers, maces and axes.
Security is another weak skill for perks, even if you put pickpocket under security.
Armor skills sounds even weaker.
We will also probably have some non skill based perks like in fallout.
Yeah I don't expect to see more than around 9-12 perks per skill, maybe ranks keep it a nice 12 granting 216 skill perks and ranks total, leaving 64 perks to be spread as challenge perks, companion perks, racial perks and whatever. 64 for the rest sounds not like a lot though.
See this screenshot: http://www.news.scrollstudio.com/wp-content/uploads/2011/02/The_Elder_Scrolls_5_-_Skyrim_Screenshot_1.jpg
where Destruction have 11 (or 10?) stars, whereas the Restoration seems to only have 9 and Conjuration 10. Maybe it can be read as the origin star being the skill itself instead of a perk, in which case you can subtract one perk.
If so that could leave us with a nice even 10 (11 for Destruction, grrr) perks for skills, totalling at 180 (or 198), leaving 100 (or 82) for the rest.
Another could be 3 "major skills" (one in each arch category), that got 11 perks, 6 "minor skills" with 10 perks, and 9 "misc skills" with 9 perks (174 perks total) leaving 106 for the rest.