I was considering recreating a few of the common diseases with drain/damage attribute spells but it's not the same. Common diseases slowly drain attributes over longer periods of time, not really possible for a Morrowind mage to reproduce without a massive amount of magicka.
So I'm now thinking about using some real-world diseases as inspiration. From the common to the rather more fatal. These would all use damage [attribute] spells to get the effect.
I was just wondering how other people might go about it? What diseases would you incorporate and what effects would this add to the spell? Or could you personally not consider it as roleplaying if you used real-world afflictions in your game?