Basically if I check mark one more mod then 160, dosnt matter what the mod is, my game crashes on start up, anyone have nay ideas?

There is a limit on how much plugins the game can handle, but i tough it was around 200? If that is the issue you'll need to start merging mods, for example use Wrye Bash to merge some simpler mods into it's bashed patch. Don't know really know about other merging though :shrug:

255 or 256 I believe. Though I would say the majority of users' games will reach their actual plugin limit well before 255 / 256. However, instead of crashing, you'll actually experience "!" marks all around the place... or at least that's what every other user that has too many plugins has experienced.

Regardless, like ToJKa says, the solution may be to just merge your mods. The best merging tool, in my opinion, would be http://newvegasnexus.com/downloads/file.php?id=39655.

No it is crashing to the desktop (CTD) The limit is 255, I have been using mods since morrowind. I have never seen a porblem like this. I did A complete reinstall and Am still getting the same problem. So I decided to just dump some of the smaller cooler mods in favor for WMX and Prj. Neveda, etc.....Thanks for tyring to help though!

Why would you need 160 mods? I only have 17.