After completing G.I Blues Mick & Ralphs bugged. I can't get the store inventory anymore. When I ask too see what there are for sale they just say "take a look" and then nothing. No inventory, just the normal topics.

Also after I killed Benny in fair fight at Ceasars fort, I talked to Ceasar a bit, there was 3 options, Kill Mr. house, Im done working for you and Good bye.
I chose good bye and for some reason that was same as choosing Kill Mr. House. Caesar wont talk to me anymore and quest was updated to kill Mr. House even I didn't choose it.

There are tons of floating trees, rocks and other stuff in the world. Some areas seem like Obsidian didn't finnish them in time.

There seems to be noway to complete whitehand after I took care of their cannibalism thingy. All is left to ignore them.. Talked to every NPC in whitehand and no new missions or notes or anything. Same goes to BoS and Khans. Didn't even get any missions or anything with Khans. Just talked few topics and that was it. With BoS i did all the missions I got from there and then had a chance to joined BoS, joined and then ignored BoS. (I quess that if you leave mcnamarra in charge theres only ignore option.)

The Thorn seems to cause CTD to me if I try to fight in the arena. Tried dozen times, CTD after match, didn't matter what critter I fought or how many.
The NCR cook side mission is bugged too. I fixed the food prossixr, got them the meat and the spices etc and Cook told me thanks and thats it. I still got topics with the cook like where I can find spices or how I fix the food prossesor.

Companions are bugged in every way. They wont stay passive, they sometimes don't even wait. I tell them to wait here and soon they are following me again. I told them to wait here dammit and after few mins they are following me again. As I play on hardcoe I think that im gonna feed them all to a pack of Deathclaws, Im better off alone.

The bug with getting stuck with "how little we know" mission is completeable by killing Nero and Big Sal yourself. They are waiting the mission trigger in Vip area at Brimstone part of the Gomorra.

What else? Well Shu at NCR told me about a NCR ranger stash or something but threres no map marker of anything. Tried to follow his leads to location but could not find anything. Found dozen other minor locations that seems to contain... nothing!

Thats about it.