Right now I am trying to optimize my gameplay experience. So are these mods sufficient to balance everything out?

Oblivion.esm
Francesco's Leveled Creatures-Items Mod.esm
Francesco's Optional New Items Add-On.esm
Oscuro's_Oblivion_Overhaul.esm
Mart's Monster Mod.esm
Enhanced Daedric Invasion.esm
FCOM_Convergence.esm
AFC v2 Core.esm
HorseCombatMaster.esm
Unofficial Oblivion Patch.esp
UOP Vampire Aging & Face Fix.esp
DLCShiveringIsles.esp
Unofficial Shivering Isles Patch.esp
SM Plugin Refurbish - SI.esp
Francesco's Optional Chance of Stronger Bosses.esp
Francesco's Optional Chance of Stronger Enemies.esp
Francesco's Optional Chance of More Enemies.esp
Francesco's Optional Leveled Quests-SI only.esp
Francesco's Optional Leveled Guards.esp
FCOM_FrancescosNamedBosses.esp
AFC v2 Combo Chains.esp
AFC v2 Combat Moves.esp
AFC v2 Quick Powerattacks.esp
AFC v2 Damage Text.esp
AFC v2 Gauntlet Weaponry.esp
AFC v2 Locational Damage.esp
Enhanced Economy.esp
C&C - The Blackwood Company.esp
DLCHorseArmor.esp
DLCHorseArmor - Unofficial Patch.esp
SM Plugin Refurbish - HorseArmor.esp
DLCVileLair.esp
DLCVileLair - Unofficial Patch.esp
DLCMehrunesRazor.esp
DLCMehrunesRazor - Unofficial Patch.esp
SM Plugin Refurbish - MehrunesRazor.esp
DLCSpellTomes.esp
DLCThievesDen.esp
DLCThievesDen - Unofficial Patch.esp
DLCThievesDen - Unofficial Patch - SSSB.esp
SM Plugin Refurbish - ThievesDen.esp
Bob's Armory Oblivion.esp
FCOM_BobsArmory.esp
Loth's Blunt Weapons for Npcs.esp
Oblivion WarCry EV.esp
FCOM_WarCry.esp
Oscuro's_Oblivion_Overhaul.esp
FCOM_Convergence.esp
FCOM_RealSwords.esp
Mart's Monster Mod - More Wilderness Life.esp
Mart's Monster Mod - Extra Wounding.esp
Mart's Monster Mod - Zombies for Body Meshes.esp
Mart's Monster Mod - Dungeons of MMM.esp
Mart's Monster Mod - Gems & Gem Dust.esp
Mart's Monster Mod - Hunting & Crafting.esp
Mart's Monster Mod - Farm Animals.esp
Mart's Monster Mod - Diverse WaterLife.esp
C&C - The Blackwood Company - OOO.esp
OOO-WaterFish.esp
DLCFrostcrag.esp
DLCFrostcrag - Unofficial Patch.esp
SM Plugin Refurbish - FrostCrag.esp
Knights.esp
Knights - Unofficial Patch.esp
Mart's Monster Mod - City Defences.esp
Enhanced Daedric Invasion.esp
EVE_ShiveringIslesEasterEggs.esp
Quest Award Leveller.esp
Alternate Start Revamped.esp
SM Encumbrance and Fatigue.esp
SupremeMagicka.esp
SM_ShiveringIsles.esp
SM_EnchantStaff.esp
Duke Patricks - Actors Can Miss Now.esp
RealisticLeveling.esp
Stat Restore.esp
Arena betting.esp
bgBalancingEVCore.esp
Bashed Patch, 0.esp
DeadlyReflex 5 - Combat Moves.esp
SM_DeadlyReflex.esp
Duke Patricks - Combat Archery.esp
FormID Finder4.esp
Oblivion Graphics Extender Support.esp

Yes I do not know how to make the spoiler tab. Go figure.

Balance is somewhat subjective. Does it feel balanced to you?

I read the combat balance thing. Everyone was picking this mod and such. As a sidenote is it a good idea to have the increased spawns module?

Your mixing AFC + Deadly Reflex + Duke Patrick.

I'd bet if you even go so far as to ask the authors of these mods if they would balance each other out the answer would be no.

AFC has some bugs as far as I know and and certainly mixing it with DR is like mixing coke and pepsi.

I'd expect ctds with that combination.

Otherwise balance is the most subjective topic. And again DR is more arcade-trick fighting while Duke focuses on combat realism. So again you will see combat every which way up to ctds in melee and harsh realism in archery.

These are not made to work together like OOO and Frans are with FCOM.

I I am using realistic fatigue also so what overhauls are recommended to use for it?