I've tried a lot of builds. But this is the best one so far for hunting deathclaws

2 intense training str
4 radchild
6 bloody mess
8 toughness
10 toughness
12 hand loader
14 adamantium skeleton
16 purifier
18 paralyzing palm
20 jury rigging
22 grim reapers sprint
24 piercing strike
26 action boy *
28 action boy *
30 better criticals *

str 8
pe 5
end 9
cha 1
int 7
ag 5
luck 5

traits: trigger discipline, heavy handed

skills: guns 100, unarmed100, sneak 100, repair 90, survival 70

gear: sniper rifle&silencer, balisitc fist, gannon family tesla armor

* you must have implants for these perks, but you have all the time to get them.

Deathclaws still pwn me with all that x).

Just for a laugh I charged at one wearing only under pants and armed with a rolling pin, did not end well.

Anti-material rifle, incendiary rounds, lots of Steady and Psycho, and a high vantage point. That's the only way I could clear Quarry.