Starting over from scratch
I would love to run
OOO
MMM
Fran
(FCOM) all together -
But would also like to run Better Cities and Unique Landscapes together
Will this be okay?

I'm starting a fresh install - so there are no mods as of now!

Thanks

Yes, it will be fine if you follow the proper installation guidelines and any grab any possible compatability patches you might need (there's atleast 2 UL's that need patch to avoid issues with OOO)

Here is a list of the things I have so far:
(DLC list first) - Fighters strong hold - knights of the nine mehrunes razor - orrery spell tomes thieves den vilelair wizards tower

I have cobl_172-21104.7z
OBMM
OBSE
Mobsified DCL 19203.rar
Oblivion v1.2.0416 (english)
Shiveringisles 1.2.0416
Unofficial Official Mods Patch v15 (installer)
Unofficial patch 3.2.0 installer
unofficial patch supplemental 27710.7z
unofficial shivering isles patch 140installer
TES4lodgen 3015

I believe that's all need?

You'll need Wrye Bash to be able to get FCOM and COBL to work properly.

Otherwise, install things properly, use the right patches (and don't go overboard on your graphics settings if you are on a weaker computer) and you should be fine.

I would also grab Streamline (for purging and saving) and OSR (for smoothing), if I were you. BOSS, definitely. Plus a bunch of "must have" little gameplay mods (very subjective, mind you). For example, Toggleable Quantity Prompt. And some things like Fast Exit 2, etc. Basically, check out http://tesivpositive.animolious.com/ and you won't go far wrong.

Anyway, I've been using FCOM plus all the ULs and Better Cities for some time, and they're absolutely fine together. Oodles of patches later, sure , but it's worth it, IMO.

I have the new BOSS and Wrye Bash
Yeah, those are a must!

So far, the things I have listed should be fine!?

You shouldn't have a problem. They're all mods made by quite teams and will work well and work well together. I'd recommend a magic overhaul for this mix plus Midas magic, but that's just my opinion.

Yes.