There's a mod called OFF - Optimized Facegen Files. Just do a search at TesNexus for "Optimized Face" and it'll come right up.
This minimizes the "cross-slider interplay" amongst other things. It also helps to minimize neck seams and has improved age texture overlays.
If using OFF gets you interested in otherwise improving PC/NPC faces and bodies, you may want to see http://www.gamesas.com/index.php?/topic/1170609-how-do-i-make-body-seams-as-unnoticeable-as-possible/.