Hello... I really like to play oblivion, boosted with some mods but i cant really make it work properly...

My computer is a pretty new machine with good graphic card and much memory.
Today I installed the game after a long time
I have installed Unnoficial patch (latest), and streamline
I use OBSE latest
I use Oblivion Mod Manager and BOSS
I also use 6-7 mods i like (Deadly Reflex, OOO, Share/Recruit, Some weapon mods,and visual achantments
And i have resently done Defrag to my disk

I start play and my Oblivion crashes on every battle I m trying to make.
Even if I have 1 mod or 20 I get the same thing!

What is wrong for god's sake? (!)

1) This surely belongs to the Mods section of the forum.

2) Post your load order in order to be easier for all of us to determine the problem.

This is my current list, because i have removed many of my favourite mods to make it more stable

Oblivion.esm
Oscuro's_Oblivion_Overhaul.esm
ShieldOnBack.esm
Toaster Says Share v3.esm
Tamrielic Ingredients.esm
HorseCombatMaster.esm
Unofficial Oblivion Patch.esp
TES3 Refugees.esp
Morrowind Ingredients.esp
Tamrielic_Ingredients.esp
Tamrielic_Ingredients_OOO.esp
UOP Vampire Aging & Face Fix.esp
TSS Custom Companion Template.esp
Oblivion Citadel Door Fix.esp
Oscuro's_Oblivion_Overhaul.esp
Shield on Back Plugin - OOO.esp
Shield on Back 3.1.esp
Visual Enchantments v1.0.esp
DeadlyReflex 5 - Combat Moves.esp
Alternative Start by Robert Evrae.esp
Crossbows of Cyrodiil.esp

Have you installed the Hotfix for Deadly Reflex 5.0? Also, try putting it at the very bottom of your load order and try combat again.

Also, make sure you're using the latest OBSE version (currently, 20).

Make sure you have all of the resources the mods you are using require, your problem might be a missing OBSE plugin that a script for Deadly Reflex or Shield on Back needs to work.
EDIT You might consider trying an earlier version of OBSE, some older mods do not work right with a newer version of OBSE, try version 19 instead of 20. The version that was current when a mod was made will almost always work for that mod, but this can cause you to have problems with mods that are made for the latest version of OBSE. You can use the information in the readme to determine which version may fix your issues.
EDIT # 3 Follow Thoma Kairas' advice.

I made some research.... and I made a comclussion.
I have resentrly made a custom own mod that adds a building, furniture, some npcs and some scipts on them.
When i deselect it, my game is snot crushing anymore (at least not often).

The prob is that i really like that mod...
Is there any way to fix it?

Probably scripting errors or broken AI packages. You might want to check out the classes on Scripting and NPCs at TESAlliance http://tesalliance.org/forums/index.php?/forum/82-esiv-oblivion-school/

I clean my mod using TES4Edit and i found some "dirty" staff in there. I havent noticed any real conflicts there, only ovverides that cause no prob. I removed whatever was wastnt in use, my game still crashes...
I dont know... maybe finally that wasnt the fault.

You suggest scripting problems eh? During the battle my mod is not "working" anything than npcs, and i m using some other follower script (Share/Recruit).

If a script has not been set up properly, it is going to cause problems. It doesn't matter when your mod is "working" anything, if a script has, for example, bad conditions, it is going to destabilize the game because it can't be executed properly.

Scripting is probably the most touchy aspect of modding this game, therefore I suggest you either go back through your scripts very carefully to debug them (including the scripts used from that other mod, there may be script errors there, too), or post the scripts in the CS forum for someone with more experience to review.