Since I play exclusively in 1st person (and the 3rd person camera can't even be pulled back very far in NV) I want to be able to scroll through my weapons with the mouse wheel; just like with any other shooter. Now, I know if this was added in a mod, it would mean being required to place your weapons on hotkeys and it would scroll through those keys. But adding in the ability to weapon scroll in the game itself could allow you to simply scroll through every equippable weapon in your inventory, which would free up those 7 hotkeys for chem use.
Please consider this; someone. Mod makers, Obsidian, Bethesda.... It needs to happen.