So far I'm at the part in the brotherhood questline where you have to find the three holotapes. I've found everything that I've done recently to be very difficult. For example, that slave camp that Caesar was at would've been down right impossible to go through without going on very easy mode. It's probably because of my armor ( still in Van Griff armor that you get from the Silver Rush Questline and it's in poor condition ), or the fact I'm still using a hunting rifle, or maybe it's just I'm to low of a level to be at this quest line ( I believe I am level 12 ).
Also I found getting to one of the holotapes to be a very difficult challenge. I had to go through the super mutants and they were packing. They all had decent weaponry like an incinerator or some type of machine gun.
And don't even get me started on my encounter with the Boomers...
One of these days I'm going to try to play through on Very Hard + hardcoe with the best build I can find.
Anyone agree that this game is much more difficult than Fallout 3?