what i'm talking about is holding/grappling, imagine if you will that you could use your unarmed hand to hold an opponent by the neck or arm immobilizing the opponent for a few seconds, in those few seconds you could strike the enemy with your other arm (armed or unarmed).
while sneaking you could use your hands to perform a chokehold to your opponent rendering him/her unconscious instead of using a dagger to kill.
these maneuvers would only be effective on humanoid enemies though.
if you have any other ideas on this could work feel free to post
if you disagree please post the reasons why and preferably give feedback for a better solution or other ideas.