ok my question is what if i kill mr house kill ceasar kill ncr ambasador and lady in charge at dam does game end now that end mission cannot be finished ? oh and kill yes man as well

Good luck keeping Yes Man dead

ok i see your point but killing the others. what happens does game crash. i was told it had 5 possible endings so far ive done ncr, 2 different independant ones. and mr house tho i so wanted to kill him for making me wipe out certain factions.

It's perfectly acceptable to take out the primary NCR officials, the upper echelon of the Legion, and Mr. House. The game world won't break, in fact the only repercussion is that the main quest can only be completed through Yes Man.

There's actually a challenge perk that requires the death of Caesar, President Kimball, and Mr. House (and the King). Granted President Kimball's death doesn't hamper any quest line and it's possible for Caesar to die without affecting any quest line either . . . obviously you can't kill Mr. House and continue with his quest line.

You also have to eat their bodies!