Which weapons do you have?
What perks and skill levels as well?
The best tactics are at range with AP bullets.
A scoped weapon when crouched, silenced if possible.
Other weapons that will have good effect are.
Light machine gun, AP or .223 rounds.
12.7 pistol or smg normal rounds.
Hunting or Riot shotgun slug rounds, with shotgun surgeon for max effect.
Sniper rifle AP rounds.
Hunting rifle the same.
Anti material rifle any rounds.
Brush gun normal rounds.
Take pscho, jet, med x and buffout, as well as any self made chems.
The perks that help the most are better criticals and finesse.