Oh I have, many times.
But it's not quite the same. It gets darker, but often the sounds aren't there. Plus for half of it all I mostly hear is the "you're taking radiation!" sound. hehe
Two Worlds-1 may not have been anything more than a light & fun (well, fun to me, I know many here probably hate it) hack n slash romp, but I loved running around in the rain in that game. IIRC, Morrowind was cool in that regard too, for the time at least.