SPECIAL (I ride the short bus, baby!
)
VATS (Short of removal, how do you solve this with an MMO?)
Perks
Non-Linear World Exploration (Tactics was a mistake in this regard)
3rd Person Perspective (wouldn't mind a shifting perspective somewhat akin to NWN)
50's optimism & old-tyme feel meets post-apocalyptic pseudo-steampunk thematic elements.
Corvega, Nuka Cola
Power Armor
Brotherhood of Steel.
The Enclave
Super Mutants (Why isn't there Power Armor for them like the last boss in F2?)
Ghouls (I'm going to miss Harold - if Bethesda's F3 is canon, will there be a difference between FEV ghouls and rad ghouls?)
FEV, GECK, Vault-Tec Vaults
PIP BOY!!
I loved the hummer and party-play elements in Tactics (I know it wasn't F1 or F2, but...)
And, will players have the option of choosing to play a Robot, Ghoul, Super Mutant, Vault Dweller, etc?
What about joining organizations, such as the Enclave and BoS and Followers of the Apocalypse, etc?
The questions... oh, the many, many, many questions...