Emperor Uriel Septim: "I go to my grave. A tongue shriller than all the music calls me."
Me: "...No, I mean, right now, where are we trying to get to?"
Isleif the Open Handed: "Well don't expect a handout from me. You certainly don't need it. I share my good fortunes with the poor and needy, and you ain't neither."
Me: *just out of prison, wearing rags, has only a few gold to name* "What are your standards?"
NPC: "You smell of death. Been conjuring up dead things?"
Me: "How DARE you accuse a member of the Mages Guild of necromancy! I conjure up Daedra, thank you very much, and if you're not careful I'll do that right now."
And an out-of-character bit:
Martin: "Have you brought help? We've been trapped-"
Me: "OHMYGODOHMYGOD It's Sean Bean! :wub: *contented sigh*"