One thing I found that Fable lacked over the TES universe is the changes in scenery. Being a big dust bowl restricts it.
The fact is when I have watched documentaries on the Discovery channel about what would happen if and after there was a nuclear war, is that nature will quickly adapt and will re-claim the earth back.
This research was discovered by scientists studying Chernobyl in the Ukraine which was subject to a nuclear leak. What amazed them was how quick and how easy nature adapted and actually thrived with the absences of mankind destroying it.
My question is, would you like to see more of a natural universe beginning to appear. Trees growing up and into building and herds of mutant cats with flying abilities like a flying squirrel (watch the discovery channel to understand this one - about how they think the cat will adapt and evolve)?
look it up or try and find the documentaries on the net to see what i mean