Pretty much gone apart from outposts in Chicago allueded to by Whitley in ED-E's logs. More than likely these outposts were formed during the exodus from Navarro to Raven Rock or were formed sometime after, in either event there existance indicates that the Enclave still exists rather than the Enclave has gotten larger.
There are some who would will you too believe illogical fantasies of the Enclave having bases across the globe because of one line in the Fallout Bible which defies logic and canon and has not been confirmed; when Rook or Enclave Mk II shows up to contest this idea I will seek to prove them otherwise - again.