I'm guessing no . Which is a shame, because they are by far my favorite weapons. Don't like automatic weapons, or any of the energy / big guns.

If only you could aim for the eyes, fallout 1/2 style... I completed f1 with nothing but a desert eagle once, by always aiming for the eyes and getting all the crit perks. But I can't see that working in this game.

Heck yeah it's possible. I've roleplayed a character who has done this, and believe me it can work.

You could... Get ol faithful some stimpacks and power armour and you’ll be fine.

It would be a cakewalk on very easy...

Hmm, how did you deal with groups of enemies indoors with limited room for maneuvering?

Run, reload, have some stimpacks handy.

Small guns
Medicine
Sneak

That's the build. It's very fun.

Just run away. If only they had a nice semi auto gun.

EDIT: I don't remember if there is though...