Either that, or put a script on the door leading to the interior cell, that has a startquest scripted.
I started this method but ran into the issue that the door wasn't doing it's normal processing after activating and the script was firing OnActivate so the player saw the quest before entering the home.
However, I used this in a different way and solved it. I found a static candlestick I have placed on a table and placed the script on that instead using the OnLoad. This way the player enters the cell, loads up that object, and the quest pops open. Although, I can't imagine this is the best way to do this, there's got to be a more elegant solution...