(Yes, this is a repost of my post on thenexusforums. But I thought I'd try to reach a bit more of the crowd)

Right, so I felt like replaying New Vegas again and I sat out to gather up the mods that I used in the past and a few new ones as well.
At first I had no major problems. Just a few random crashes that I have come to expect from this game. Wasn't really that bad but now half-way through the game it has become a lot worse.
Instead of just crashing when entering a new area or leaving one. I am now randomly freezing as well. I thought it might be a mod problem so I went out and disabled all mods, got back in and started to fast travel around a bit to see if it would be better and that seemed to help it. So my next thought would be a mod conflict or a load order conflict. And since I'm no expert on that I thought I might as well seek out someone that does know more about it.

So my load order would look something like this. (Using FOMM)

More Perks.esm
More Perks for Dead Money.esm
FalloutNV.esm
HonestHears.esm
More Perks for Honest Hearts.esm
OldWorldBlues.esm
More Perks for Old World Blues.esm
Primary Needs Hud.esm
Project Nevada - Core.esm
Project Nevada - Equipment.esm
NewVegasBountiesII.esp
UHNV.esp
UHNV-Dead Money.esp
UHNV-Honest Hearts.esp
More Perks for Dead Money Update.esp
Sorter - Combined.esp
CONELRAD 640-1240.esp
NovaMod.esp
GhostGoggles.esp
NewVegasBounties.esp
Project Nevada - Dead Money.esp
Project Nevada - Honest Hearts.esp
WeaponModsixpanded.esp
More Perks for Honest Hearts Update.esp
More Perks Update.esp
NVWillow.esp
More Perks for Old World Blues Update.esp
Project Nevada - WMX.esp
Expensive2.esp
CASM.esp
QS_Blackwolf_NV_Backpackmod.esp
Brotherhood and House Alliance.esp
AllCompanionsEssential 2.0b.esp
Readius_NV.esp
Project Nevada - Cyberware.esp
Project Nevada - Rebalance.esp
The Mod Configuration Menu.esp

I am also using NMCs_Texture_Pack_For_New_Vegas (Medium Version)

The specs I'm running on are:
i7 960 3.2GHz.
12GB 1600MHz ram.
GTX 480 1536MB.

Drivers are up to date.

I did try got get CASM for my saving needs instead of the default ones to see if that helped out but I'm not quite sure if it did. If so, it wasn't very noticable.
I have been using the fnv4gb, NVSE version.
I have tried running both in fullscreen and windowed mode without much of a difference there either.
I do run with two monitors, I haven't tried disabling the second one yet, I've heard that does help out with some stability, is there any truth in that?
Also, I remember something about crashes being more frequent if you have the radio playing when switching zones, true or false here? I -think- I have noticed a few more crashes with the radio on, though that might just be an illusion.

Any help would be welcome!