Had the same problem with hacking, not with lockpicking tho. Fuzzy looking screen and can't see any words on the screen.
I'm not too far in the game yet, but my first issue with hacking was in the schoolhouse in the first town. I couldn't hack because of my low skill, so I used Mentats and a Skill Mag to get my skill up enough, and then when I activated the computer it didn't even go into the hacking screen, it was just jarbled letters saying that it was an inactive computer.
Then I reload my save from before I even tried any of that, and when I walk up to the computer, it doesn't even say it needs to be hacked, and when I activate it the same jarble comes up.
I eventually restarted my game for SPECIAL reasons, and when I went to hack the comp a second time everything worked fine.