I never got the point of the drugs in these games though. Its fun just because it's illegal and entertaining, but doesn't it just bring down your intelligence while adding to your strength? It just seems like a potion.
All you need is a pot of boiling water, some baking soda and... I don't know the recipe, but you get the recipe to make Skooma from various underground hip-hop artists around Tamriel.
The first dude I met while playing oblivion. Walked all the way to imperial city (didn't know how to fast travel yet) and came across a drug dealer. Needless to say I killed him and robbed his corpse.