I don't think it's a corrupted save - as it does not say it's corrupted. Apparently it thinks the DLC is no longer on the HDD and then it says the save device not detected or something.
It seems majority get this problem from the Come Fly With Me quest. In cases related to the space suit.
After the patch will I still be able to load my save, or is it one of those deals where "oh, it just won't happen again, but your save is useless, have FUN starting over!!" That's 33 hours gone. And I was playing on hardcoe + Very hard mode.
But the biggest question is when is this patch coming? If it's not going to be fixed until weeks later, I might as well just trade this game in for Fable 3 or something. I understand it's hard to give dates, but I (and a quick search on the internet, tells me many others) are having this problem as well, a game we spent 60 to 85 bucks for to be able to play day 1. At least you can give us a date so we know what to do with your product.