- The obvious stuff: Force yourself to sleep every night. When you sleep, take your armor off and wear clothes that resemble pajamas. Take off boots and helmet. If you can't sleep over a period of more than 24 hours, poison yourself with something, to simulate tiredness and lack of sleep. Try to have 3 meals a day. If the quality of the meals you're eating is inferior, simulate lack of nutritional diversity by: If you contract a disease, wait a bit before curing it, to simulate a weak immune system.
- Vitamins: When I wake up every morning, I take one minor potion of healing and one minor potion of stamina, to simulate taking "vitamins and supplements." After all, we're trying to be a hero here.
- "An apple a day keeps the doctor away" - Eat an apple every day when you wake up.
- Learning about the world: Read at least one book a day, either during lunch or before sleep. Don't carry more than 5-6 books with you at any time, store them somewhere. Books are heavy and a warrior needs to carry other things, even if he/she is a warrior/scholar.
- When living in the College of Winterhold, or when sleeping/living in any share quarters, "lose" some things to simulate a [censored] roommate stealing from you, especially food.
- Before you leave a town, pray at the local shrine to simulate asking the gods for success.
- If you unintentionally hurt a companion, part ways with him/her to simulate a falling-out.
- If you kill an enemy and you respect their courage in combat, do not loot them. Instead, place their body in a proper, dignified pose and place some mountain flowers near the body.
- Do not hunt/kill animals unless they attack you - be an environmentalist.
- Do not eat any meat - be a vegetarian.
- Do skooma at least once a day, or drink a few bottles of wine/ale at night to simulate drug use/alcoholism.
- "Pickpocket" women to simulate sixually harassing them.
- When you go dungeon diving, force yourself to either use a torch or a light spell.
- Be a part of only one guild at a time.
- Sell your soul/fool the gods: Either keep all daedric artifacts, or return all of them.
- If you find yourself outside, traveling long distances in inclement weather, poison yourself to simulate catching a cold.
- Remember how armor and weapons wore down in Oblivion? Simulate it in Skyrim to the best of your abilities.
- Work at the smith/lumber mill at least a couple of hours a day to simulate having an actual job.
Etc, etc... Add to the list!