I originally made the mistake of using both the esm and the existing esp and trying to make another esp from that. That thread is here:
http://www.gamesas.com/index.php?/topic/1287483-weird-cs-esp-access-problem/page__p__19434588__fromsearch__1#entry19434588
long story short, I decided the best fix was just to edit the existing esp to my taste and save it. But it's still not working.
I'm selecting Oblivion.esm and EM_RedRoseManor.esp. I'm selecting the esp as the "active file". But when I got to save my changes nothing happens.
I haven't fooled around with the CS in years and I'm getting really frustrated. Thanks very much for any help!