Shadowrun, wow. theres a really underrated game there.
Kinda wish that studio had not shut down after its release . But yes i did like their quick mapping in that game, once you got used to it it seemed to flow easily with the pace of combat even in a fps.
It's nice to hear from someone who enjoyed Shadowrun -- I still play it quite often.
I also want to point out that there is the up angle left/right and down angle left/right that they could as well allow you to set another category of skills/spells/items in.
Not to mention, the right shoulder button (consoles) does nothing that I'm aware of -- combined with the fact that a 'sprint' mechanic could be implemented by simply keeping the thumb stick pressed at full tilt for a second or two...you'd essentially free up both shoulder buttons to map items to the corresponding triggers.