Recently I've been having a strange problem with Morrowind Comes Alive. Whenever I approach the city of Caldera I get an error message telling me that an MCA drunkard had no animation class. When this happens my only option is to click "OK", which then crashes the game. This happens every time I go anywhere near the city without fail. I tried reinstalling MCA, but that didn't help. My character makes his home in Cadera, so this is starting to get annoying. I went into the construction set to fix the problem, but as far as I can tell all of the MCA NPC's have they're proper animation class. Does anyone know what the problem is and how I can fix it?

This is what I'd try:
1. open your Warnings.txt and get the exact id of the NPC causing problems (e. g. _MCA_drunkard_ex_bosmer)
2. create a Mash text file http://wryemusings.com/Wrye%20Mash.html#Remove (e.g. mca_dunkard_remover.txt) containing at least one text line with your NPC id and name (e. g. like this):

# [Filetype: Wrye Mash Remover]# MCA 6.1"_MCA_drunkard_ex_bosmer"	"Drunkard"

3. read Mash info about removers and apply to your save, you should be able to get rid of the NPC references

Thanks. I made a remover to remove all the exterior MCA Drunkards and the problem still persists. I checked my warning file and all it says is that the id of the character causing the problem is "CVdrunk00000000". That doesn't seem like a MCA NPC to me, but I don't have any other mods that add drunkards to the game.

Here is the exact text of the warning if that helps.

"Actor Animation problem with "CVdrunk00000000".
This actor has no Animation class!"

EDIT-Morrowind Animation Kit showed me what the problem is. Turns out MCA wasn't the culprit, it was a mod called Tamriel Realtors. I disabled the mod and the problem disappeared.

So we know now it is not from MCA,,, some progress.
Try this.
First, check if there is a reference to CVdrunk (the 8 digits are the progressive number of the reference id so they are not part of the id) in your save (you can use any tool able to search a text inside a file, e. g. http://www.nirsoft.net/utils/search_my_files.html, http://www.wingrep.com/download.htm, http://mh-nexus.de/en/hxd/, thttp://www.ghisler.com/ or even the ugly Windows search).

If there is a reference, it may be from a mod that you removed. I assume you already tried a "repair all" with your save in Mash, so I'd try a Mash remover like this

# [Filetype: Wrye Mash Remover]# ?unknown"CVdrunk"       ""

I don't know if it will work with just the id and not the name, but it is easy to try so why not?
You could also search for any file in
data files\*.es?
folder containing CVdrunk text, if you find the mod you can also find the NPC name for the replacer

If you are using FPS Optimizer, try without it and see what happens.
Also, after crashing, open the Morrowind\Warnings.txt file and post the exact error message here, there may be some other detail

[EDIT]Ah, you have found the culprit already! nice