I haven't had any issues with arrows on my thief but when trying a mage I noticed that the dot dead on an enemy ended up missing on my cast. I have to aim just to the right of the mobs. Anyone else seeing this? Any way to "enhance" casting to make it a little smoother (not necessarily easier) to actually target and be able to hit before the enemy gets in melee range?

not really....if you noticed though, when you fire a fireball, it spirals forward especially at a distance.

If you mean the blasting type spells, like Flame...nope, cant say ive noticed any inaccuracy :S

fireballs swirl a little bit, ice spears fire straighter than an arrow, and lightning is a sniper rifle