Only one I considered straight up murdering was Maven Black-Briar.
I did it, then decided it was just the idea that appeased me and reloaded. Also figured the thieves guild wouldnt like it much, especially since I'm their leader = /
I was travelling and there were some random noble-types going to a wedding or something. I just asked whats up, [censored] was unreasonably rude. She took a flaming swan dive off the nearby water fall. Her man and her useless bodyguard.
Some Thalmors dragging some prisoner round, and some Imperials dragging a brother Stormcloak.