Having used various perks, which perks do you wish you hadn't picked?

Mine are: 1) Destruction perks (spent three here that I wish I could get back) AND 2) Deflect arrows (I no longer care about avoiding arrows or elemental damage with my shield)

Lockpicking, so many picks, and the perks really aren't that useful. 2/5 in the base Sneak could easily be 1/5. Probably don't need more than one point in Crit Shot in Archery.

The one that removes weight of armors. Its bugged and sometines turns off so just to be safe i dont use the extra carry capacity anymore. And i had to take the useless punching perk just for it.

I'd take a few away from sneak. I don't like crouching down in the middle of a fully lit room and not being detected by NPCs looking right at me. It just feels cheap.

none, cuz i am SMRT S-M-R-T and don't pick dumb perks

The armor perks in alteration. I did not know that the end armor spell in the alteration tree would be more powerful than any of the other armors even with the perks and it would also be incompatible with the perks. Farking moronic that the end spell completely devalues the perks which are supposed to show a focus in the tree.

I think a lot of people look at the perks the wrong way. It's not about having the most god-like character at the end when you have invested 100 hours. Like most things in life; the journey is the destination. Some perks are only usefull for a window of time until you progress beyond them. That doesn't necessarily mean that you should regret getting them. Unless, of course, you're talking about lockpicking perks (which are completely unnecessary).