Yeah I know that, but still I don't know if one handed affects Fists it would make sense tbh if it does :toughninja:
I think the aforementioned perk in the Heavy Armor tree is the only perk that affects unarmed damage besides the Khajiit racial trait.
The whole point, I suspect, is to reduce the effectiveness of unarmed fighting as a legitimate combat style. (notice they don't even have a skill tree for it anymore.)