And his second, and third-hand man. I world traveled to the fort, and killed them.
Does this affect the story line? What happens when I finish for the NCR, and there's no Lucius to fight? Or does it spawn a new lucius?
Do you mean http://fallout.wikia.com/wiki/Lanius
If so, you still fight him if you side with the NCR, and killing Ceaser does affect the story, but not in a bad way if thats what you are implying.