Different play styles will call for different aid. As will different races.
Sword/shield builds have you up close and personal. This means you're subjected to Mage blasts and critter bites.
Personally, I prefer to use elemental/poison/disease Resist enchants rather than any skill Fortify enchants.
Examples:
1. A Nord would benefit from a Resist Fire enchant whilst Resist Frost is almost redundant. Exact opposite for a Dunmer.
2. Some races have natural Poison resistance, but others could definitely use the help.
3. All races can benefit from Resist Shock.
As stated, using Resist enchants is my personal preference for all my varied race builds.
To each their own, I suppose. Just remember; in a single player game, there is neither right nor wrong. Go with what gives you the more enjoyable experience.