Just read a topic discussing grenades. Yes they can be a mixed blessing. But one thing I got well into with my last character was the Mercenary Grenade Launcher. Best used with an explosive obsessed character.

Used properly, you can be very powerful with a 40mm grenade launcher. And it is great to use, working out the angles. With the long barrel mod it is even better, fires for miles. You can obliterate enemies before they even know where you are.

Or for the real enthusiast there is the Grenade Machine Gun. I don't even use it like a machine gun. Just position myself on a high peak overlooking an enemy infested spot and lob grenades one at a time, correcting the trajectory between each shot like some sort of minor artillery piece.

I'm surprised they aren't more widely recognised as killer accessories.

Yeah I love using grenade launchers. I wiped out a whole bunker of Brotherhood of steel with a 40mm.

My shotgun/explosive character was the funnest playthrough I've had so far. Thump-Thump was my heavy hitter, and it was awesome. It's just so satisfying obliterating a group of enemies with a couple of lobbed grenades. Also, bouncing them off walls and around corners is the perfect sneak attack.

Definitely, explosives are great in this game. Powerful, and satisfying to use.

Mercy.
I win.

40mm is great against most things but not all. Deathclaws, Super Mutants and Nightkin are not easy to kill with grenades.

Best use of Explosives is against Cazadors and Nightstalker packs. And Dead Money's Ghost People.

The Mercenary GL from the Courier's stash saved my life a couple times at low levels... Cripple the legs, and they're no longer a threat.

All I used it for was crippling legs really.

OMG finally someone that appreciates explosives. YES i use anything that explodes when im not struggling for making money, as EXPLOSIONS ARE PRETTY