I think it's a coincidence - the two characters are nothing alike (the one in The Wire is NcNulty's cop girlfriend, right?). 'The Wire' is also a little outside the reference pool of the creators of FNV - they seem to draw mostly on fifties and sixties pop culture (with the occasional Monty Python in Wild Wasteland thrown in).
Well Carlito's Way was 1993 so I figure anything before the game was made could be referenced, and The Wire is pretty much one of if not THE best crime dramas ever made.
I know it seems like a stretch but is this confirmed or even asked anywhere on the net? I mentioned it wasn't in the wiki (like Carlitos Wayne), so I guess no one's seen this connection anywhere? Not rly a big deal I was just curious.. and yea Beatrice is McNulty's girlfriend