hell yeah! I would love to be among their evil minds

All those goody goody factions want to help others. The scientists may work together a bit but even they would fight. It would be all about competition. It would be a blast to be in the middle of. Help them with their experiments, help sabotage their intellectual rivals plans. Hell even in the end since you know about their plans use it to your own gains and take over the scientific community by ruining their plans, or taking them over. OH hey I helped you build a Flying drone, now guess what my intelligence was high enough that I slipped a controller in and now I own them and not you. MWAHAHAHAHA.

oh snap. Or even create your own better models

Why not have a faction that is actually cured ghouls. Have someone have come up with a cure for Ghouls but somehow has adverse effects and they are trying to actually go back to being ghouls. Have it so that the cure just sped up healing but instead of stopping decay it just out healed the decay. This was bad though as it meant that the Ghouls lives where shortening because the body was healing at such a rate that it aged. Now they want to just go back to normal. A small twist on the whole curing zombies thing.

The Disciples of Knowledge-
An influential and outspoken Brotherhood of Steel Scribe named Walter Leibowitz (reference to A Canticle for Leibowitz and the name of the author of said book, Walter Miller), who was part of the Battle Mountain Chapter in northern Nevada, was angered that during the years following Father Elijah’s crime spree throughout the wasteland Scribes could no longer become Elders. He, his fellow scribes, and a handful of paladins, who did not support their current Elder who was only skilled with battle tactics, protested. In response the Elder sent a hollow threat of exile which they decided would be best. The abandon the Brotherhood of Steel and wandered for a year north to Boise, Idaho.
In Wyoming there was a man named Marcus Paterculus (named after a Roman historian) who was an influential member of the Followers of the Apocalypse. He believed recreating pre-war technology was just as important as archiving it and that if the Followers focused on more than just food and medicine they would be indispensable to the Great Khan Empire and House’s New Vegas. His superiors disagreed and after much arguing he decided to leave the Followers with only a handful of his greatest supporters, supplies (including stimpacks, gardening tools, and radiation suits), and copies of archives on advanced medicine, vehicles, tools, and weapons. He traveled along Khan controlled roads to Boise, Idaho in six months.
After Leibowitz and his followers lived in Boise for a month they met Paterculus and his followers. They had similar interests and beliefs which lead to them deciding to go northwest, out of Khan Territory and into free land, Pendleton. Pendleton was heavily irradiated, due to a convoy of trucks carrying radioactive waste being in the center of town when the bombs fell, which was no problem for Leibowitz’s power armored men and Paterculus’ radiation suits. They scavenged medicine, material, weapons, and anything else that seemed to be of use. Then they started their own settlement along the river north of Pendleton that was named New Pendleton. Paterculus, Leibowitz, and their followers eventually formed a group named the Disciples of Knowledge and their giant, private complex where they keep records of everything, build weapons and tools, and store them became known as the Monastery of Knowledge.
When New Pendleton was first getting started a lone Wastelander who used to be a member of the Followers of the Apocalypse, Arcade Gannon, showed up with a Brahmin pulled wagon containing his family’s power armor, energy weapons, and supplies. Since none at the settlement knew about him he decided to settle there and eventually told them of his past. They did not react to his background with the Enclave and when he told them of his Tesla Armor they only asked to examine it. After studying it for many long months they were able to upgrade their own power armor to make its wearer more agile and make the suit feel lighter to wear.
They will help outsiders if they can mutually benefit, they trade with the Khans and the NCR as well as the multiple factions throughout the northwestern USA.
If the game is to take place near Seattle then I think the Disciples should have an outpost there. If it is to take place near Portland I think the Monastery of Knowledge should appear in game.