I've been thinking about doing one set after New Vegas.
Idea being that The Courier met all those different groups and played a game with them. They lost, some more than others.
Idea was...
Courier takes control of New Vegas, joins with BOS and NCR to rid the Western Wastelands of the Legion.
BOS and NCR continue to pursue the Legion into New Mexico to forever wipe them out and gain new lands/tech in the process.
BOS and NCR return to Vegas to celebrate with Courier, but are ejected from the gates as the Courier has claimed it for himself.
Years later BOS and NCR have returned to their respective positions of power, though remnants have settled in Freeside and South into Spring Valley.
I had a whole introductory post ready....but then Puget Sound sounded good.