It will be made for whatever the top generation of consoles available at the time is. Or they could get smart, not sacrifice game quality, and just make it for PC.
I'll settle for it being made with the PC as the "lead platform." You can see the differences in other games, such as, say,
Battlefield 3.
It'll be good for us PC players if that's the case as, while the next consoles will still probably only make use of around 1-2GB RAM and the equivalent of a GTX560/570, it'll mean the basic common things between versions will be to a much higher standard.
I might not expect the specs to be QUITE that high... That's nearly top-end for PC, and would really be impossible for a console to integrate without selling at a loss at first: and given the Wii's dominance over the PS3 and 360, along with the necessary costs for implementing a high-capacity disk design (the Xbox 720 and Wii U will have to use proprietary designs to avoid using Blu-Ray) I find it highly doubtful that they will do this again, especially, as is seen on Sony's side, immense pressure from the myriad of investors to actually turn a better profit and regain the >70% market dominance the PS1 and PS2 had, that Sony basically squandered.
My estimates put things at a tier below that; keeping in mind that 1080p is the highest they'll bother to natively go, and that 30 fps is the standard for consoles, it wouldn't need THAT much power for many things anyway... At least at first. But falling behind PCs isn't something console-designers are too worried about. Judging this all, I'd put the GPU closer to a GT 550 (192 SPs) or a Radeon 6770. (800 SPs) The range I'm 99% certain that the consoles will fall in there would be between 128-320 SPs (for an nVidia GPU) or 320-1024 SPs. (for an AMD GPU) RAM-wise 2 GB seems all but certain; it's cheap enough that less saves about nothing (and the Wii U seems to be set to pack that quantity too) and there's not much of a push for more, though up to 4 GB might happen. The bigger question is what type of RAM will be used: it'll almost certainly be either GDDR5 or XDR2; the latter will be faster but more expensive. But given the narrow memory interfaces consoles work with, (64-128 bit, when higher-end PC graphics cards range from 256-512 bit, making them 2-4 times as potent at the same clock speeds) the extra expense for higher-clocked RAM will likely be taken. I know I'm PRETTY sure Nintendo will likely take that route, given their penchant for taking the fastest RAM they can buy, even though they never include enough of it.