limited the mods I have, etc, no textures, medium quality on what should be a high quality computer, iCore, good nVidia 3d vid card, etc, and still I have constant crash to desktop. .... I have tons of mods for Dragon Age Origins and Dragon Age 2 and they never CTD.
On higher-end computers I have much better luck using the highest-quality settings. I know that sounds counter-intuitive, but it works on the three comps I've played Oblivion on.
I agree with ToJKa: one CTD an hour is not unusual. But I have to admit, this gets to me too. Earlier this year I quit Oblivion for a month or two because I was getting too many CTDs too frequently. My Oblivion does a disappearing act: no hang-up, no error message, nothing. I'll be playing one second and the next second -
poof! - the game has disappeared and I'm looking at my desktop wallpaper, blinking, wondering what just happened.
I haven't been able to put my finger on any one factor that causes mine. My game is a little more stable now than it was when I rage-quit earlier this year. For what it's worth there are three main differences between my current mod list and the earlier one: this time around I'm not using Better Cities, Enhanced Economy and Travelling Merchants. I don't think these mods caused my CTDs but I'm beginning to suspect they may have interacted badly with other mods that I was using. I still get CTDs, but not as frequently. They're totally random. I can get one within a minute or two, immediately load the same save and experience no CTD at all, doing the exact same thing in the exact same spot with the exact same character. Or I can go for two hours or more with no CTD. There's just no predicting.
My own feeling is this this instability is something that comes with the territory. It's part of modding such an open-world game. Dragon Age (and nearly every moddable game) are much simpler games. They are linear games with tiny "maps" instead of an open world. DA:O only has to keep track of small chunks of game data at a time. Oblivion, on the other hand, has to be prepared for anything. The player can go anywhere, do anything, at any time. The game engine has to keep up with all that, it has to keep track of all that data in case it might be needed later. That's simply something that the Dragon Age engine does not have to do.