http://www.tesnexus.com/downloads/file.php?id=33114 is probably the best thought-out and executed magic overhaul but it doesn't stop being just a magic overhaul.
Less Annoying Magic Experience makes enchantments overpowered, and magic itself also gains a strong buff but it doesn't make magic itself much more overpowered than in vanilla Oblivion.
Supreme Magicka keeps enchantments in check but makes magic itself way, way too powerful.
I haven't tested Mighty Magick: Reborn yet but given the fact that it is viewed as 'Strong Powerlevel' while both latter mods are viewed as 'Medium Powerlevel' I assume it removes any challenge for mages...
If you want to play a magic user and the game should stay challenging use ROM, if you don't plan to use magic yourself but want to increase the difficulty use one of the latter mods.
Difficulty is extremely subjective and depends entirely on your use of other mods. Overhauls and quest mods can range in various difficulty as well as other combat tweaking mods that make melee and archery more powerful.
I find SM and Fearsome Magicka to be perfectly in balance with Duke Patrick's Melee Combat and Combat Archery, so everything is equally deadly. Then use a overhaul like FCOM or OWC-ND+WAC or TIE+WAC which all have varying levels of difficulty and if you still don't find it to suit your taste, adjust the difficulty slider.
I agree that LAME is overpowered for one reason, the Dremora summons are too powerful and too easy to get especially when coupled with the SM increased conjuration casting limit, 3 of those can demolish anything - you just have to run around and stay alive. I like SM just by itself.
Also I used ROM for a while and I love the magic changes in it. But it was very buggy with leveling when I played it thankfully with the latest ROMu it's very playable. The Conjuration changes are great but I just wish it was more modular, it does so much in one but I would like to use it's gameplay changes for example with FCOM on it's own.