Damn, it's quite an experience. The first thing that popped out for me was the scenery. Without the filter of health bars and AP counters, you really take the time to appreciate the world you're put in. Little details become more vivid. For example, little scrawlings on the wall, messages from people long past - "let it all end". You see the truly pervasive nature of trash and scrap, dirt and detritus.
The next thing that comes up is the renewed nature of scavenging. You cant simply swing vaguely in something's direction, and tell what it is. You cant know if a container is full to bursting, or empty as the rest of the wastes. Locks are mysteries until you try them, terminals stand indistinguishable from one another, and a thick dust presents a film which obscures everything it touches. You're forced to try every option, get up close to everything, search each individual shelf, aisle, and box. You have to scrounge in the dust and grime to simply find the supplies you need to live - literally, in hardcoe - and often can only identify by sight alone.
Then you start to get in to combat. Before anything else, you'll pine for when you could simply check your health or ammo with a short glance. No, the most you'll get is a faint indicator of when your thirst or hunger becomes unbearable, or when injuries become overwhelming. Tantamount to our own natural indicators.
When the shooting really starts, the entire process is different. You have to rely on your own perception, rather than your perception stat, to find your enemies. Corners and walls are uncertainties, not minor veils. Shooting itself becomes much more of a skill-based affair. You can no longer fire from the hip reliably, with iron sights being much more useful. Not even VATS is as reliable as it was before, as the positioning required to attack effectively with it is so much harder to attain.
Overall, I think it really changes up the game a bit. It shaves some of the veneer from what we normally interpret as a jaunty, if subliminally bleak world. It gives insight in to how people would really have to live under such circumstances, and Im not really sure it holds in line with what the game was intended as.
Still, it astounds me that such a simple change can alter the game in to something almost entirely different, and I really encourage everyone to do it, even as a temporary experiment.
Anyone else done something akin to this? I'd like to hear their experiences.