Assuming this is for a new game then you shouldn't have a problem cleaning out GMSTs before you start. Otherwise it's always best to use Wrye Mash to ensure your save is spiffy clean.
I think if you have Tribunal.esm you should enable "adventurers_tribunal.esp" to ensure the weapon and Armour balancing happens with Tribunal-added stuff. I can't see a Bloodmoon equivalent.
Thanks for the help
I tried cleaning the .esp but when i saw what i was cleaning, it was removing a lot of weapons and armors, so TBH i left it as it is.
I have one last question. i have been reading some faqs but i still have some doubts.
What would be the best procedure to add a mod like Giants (that adds creatures to the leveled lists) to an already existing game that has a merge list(mash list)
I'm level 15(role-playing) and don' want to start from the beginning.