(The following are all firsts)
TES II: Argonian warrior. I initially tired for a stealthy mage but I couldn't get past that first damn rat without a weapon as a primary skill. I did a bit with magic, but not very much, and instead focused on the fighter's guild and knightly order.
TES III: Argonian fighter/thief. This character focused more on stealth, but he stood up well in straight up combat.
TES IV: Argonian fighter/mage. I actually don't remember this character terribly well, I had some difficulties with him.
TES V: Freezes-His-Tail-Off, the Argonian fire mage. A tremendously fun character to play. He specialized in destruction magic and alchemy and pursued the mage's guild and completed the main quest. I followed him up with a high defense Breton warrior who specialized in block and heavy armor, and up next is an Altmer assassin who specializes in planting poisons.