I have traced the crashes back to Arefu Expanded. It is quite good and I can live with the crashing until I have completed the quests. So,.....

1) Load order. Any thoughts?
Fallout3.esm
ArefuExpandedByAzar.esm
Project Beauty HD version.esm
StreetLights.esm
Unofficial Fallout 3 Patch.esm
Mart's Mutant Mod.esm
Mart's Mutant Mod.esp
Mart's Mutant Mod - Tougher Traders.esp
Mart's Mutant Mod - Natural Selection.esp
DarNifiedUIF3.esp
DogmeatEssentialToken.esp
Mark and recall.esp
TenpennyGhoulsAtPeace.esp
LightweightFoodSanitizer.esp
BusworldV1.05c.esp
tubRRCompound.esp
DCInteriors_ComboEdition.esp
StreetLights - Wasteland.esp
Fellout-Full.esp
FireLightFix.esp
Fellout-pipboylight.esp
megalight.esp
ArefuExpandedByAzar-Radio.esp
GalaxyNewsRadio40[M].esp
Sydney Follower.esp
Sydney Follower - Load Order Fix.esp

2) Any ill effects to removing it, once completed?

Thanks.

Locked by OP request